AIDD-Ready Core Product Portfolio
Essential Resources for AI Drug Screening & Validation
- Affinity-Validated Target Proteins
- TR-FRET Screening Solutions
- Functional Cell LinesIP Friendly& Organoids
Efficient AI-designed antibody screening requires reliable, application-ready antigens. ACRO offers 5,000+ recombinant proteins covering diverse drug discovery targets, providing essential tools for candidate screening and affinity evaluation.
Liquid formulation, sugar- and glycerol-free. No desalting or buffer exchange required—ready for direct SPR assays.
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AIDD-Ready Core Service Platform:
CHO-Direct™
CHO-Direct™ is purpose-built for AI-driven antibody pipelines, connecting the full workflow from AI-powered design → Stage 1: high-throughput screening → Stage 2: antibody expression & purification → Stage 3: in-depth characterization → AI model iteration / preclinical development. It provides a standardized, reproducible, and iterative wet-lab framework to efficiently advance AI-designed antibodies from virtual design to preclinical development.
AIDD-Ready also includes a cell-free expression (CFS) platform for rapid production of small proteins such as VHHs and mini-proteins. With fast turnaround, CFS complements CHO-Direct™ to support wet-lab validation across diverse AI-designed molecules.
- Stage 1: High-Throughput Screening
- Stage 2: Antibody Expression & Purification
- Stage 3: In-Depth Characterization
Stage 1: High-Throughput Supernatant Screening (Rapid Candidate Screening & Model Iteration)
High-throughput validation of AI-generated antibody sequences enables rapid identification of positive candidates and efficient elimination of non-performing sequences. This reduces downstream validation costs while generating the first round of experimental data to drive AI model iteration.
Standard Workflow
Automated Report Delivered in 4-6 Days* - Day 0
AI Antibody Sequence Receipt & Analysis
- Day 1
Gene Synthesis & Construct Generation
- Day 2
CHO Cell Transfection & Expression
- Day 3
Supernatant Harvest & Testing
- Day 4
Automated Report Delivery
Core Services
Standard Deliverables
Antibody Expression QuantificationAssess antibody expression to rapidly identify low-expressing or abnormal sequences
- BLI Affinity Ranking
High-throughput affinity analysis with automated reporting for efficient candidate ranking
Optional Assays- ELISA Binding Validation
Confirm binding specificity and minimize false positives
- Flow Cytometry Screening
Cell-based binding screening for membrane protein targets
- sELISA Epitope Binning
Characterize antibody epitopes
- Early Functional Assessment
TR-FRET/ELISA blocking and binding assays for early assessment of candidate activity
Core Service AdvantagesCHO-Direct™ Platform Equipment Showcase
CHO-Direct™ One-Stop Antibody Screening & Validation Service
Starting from AI-designed antibody sequences, CHO-Direct™ provides one-stop wet-lab validation covering high-throughput expression, functional activity, and developability assessment.