Trending Searches:
My Cart
- Home
- ProductsSearch by Product
- Recombinant ProteinsRecombinant Proteins
- Immune Checkpoints
- Autoimmune Disease Targets
- Metabolic Disease Targets
- Cytokine Targets
- GMP-grade Proteins
- Cell Therapy Targets
- Fc Receptor Proteins
- ADC Target Proteins
- Enzymes
- Proteins for Neuroscience
- Multi-pass Transmembrane Proteins
- Tumor Microenvironment Proteins
- Other Proteins
- AntibodiesAntibodies
- Immunohistochemistry (IHC) Antibodies
- Antibody Services
- Isotype Controls
- Antibody Internalization Detection Reagent
- Anti-payload Antibodies
- Universal Antibodies
- Anti-idiotype Antibodies
- Other Antibodies
- Cell Lines
- Cell Culture ReagentsCell Culture Reagents
- GMP-grade Growth Factors
- Activation Antibodies
- Extracellular Matrix (ECM) Proteins
- Serum-free Cell Culture Medium
- Disposable Accessories
- Cell Culture Grade Magnetic Beads
- Nuclease
- Solutions
- Complete Solutions from Research to Clinical ManufacturingCytoPak Bag Solution for Closed SystemsCMC Production Process of Adoptive T Cell TherapiesCMC Production Process of Adoptive NK Cell TherapyCMC Production Process of iPSC-based Cell TherapyHigh Quality Laminin Protein Supports Clinical iPSC BankingExtracellular Matrix (ECM) ProteinsCytokines for Stem Cell TherapyCytokines for Organoid CultureAneuro - Neural FactorsOrganoid ToolboxKey Raw Materials for Cell & Gene Therapy
- Others
- Kits & Assay ReagentsKits & Assay Reagents
- ELISA Kits
- Autoimmune Biomarker Detection KitTumor Biomarker Detection KitStem Cell & Organoid Biomarker Detection KitCytokine Detection KitsMetabolic Disease Biomarker Detection KitINHBE/Activin E Dimer ELISA KitHuman Erythropoietin (EPO) ELISA KitBiomarker Detection KitsInhibitor Screening KitsAntibody Titer KitsAAV-related assay kitsImmunogenicity Assay KitsPK Assay KitsEnzyme-Linked Immunosorbent Assay (ELISA) ServiceBridging ELISA Kits
- qPCR Kits
- Fluorescence Assay Kits
- TR-FRET Kits
- Flow Cytometry Assay Kits
- ADC Conjugation Kits
- ELISpot Kits
- Organoid Related Kits
- Assay Reagents
- Viral Antigens&Antibodies & KitsViral Antigens&Antibodies & Kits
- Nipah Virus
- Varicella Zoster Virus
- Influenza Virus
- Respiratory Syncytial Virus
- Rabies Virus
- Herpes Virus
- Other Viruses
- ViruStop Services
- SARS-CoV-2
- Organoids-related SolutionsOrganoids-related Solutions
- Cardiac-related Solutions
- Brain-related Solutions
- Liver-related Solutions
- Organoid Culture Reagents
- OthersOthers
- Lab Reagents
- Experimental Instruments and Equipments
Search by Modality- Cell TherapyCell Therapy
- Discovery & Development
- Cell Culture Products
- CAR Targets
- Universal CAR Detection Tool
- Other Target Proteins
- General Proteins
- Drug Screening Service
- Early Pharmacodynamic Assessment
- Immunohistochemistry (IHC) Antibodies
- Manufacturing
- GMP-grade Growth Factors
- Extracellular Matrix (ECM) Proteins
- Serum-free Cell Culture Medium
- Disposable Accessories
- Cell Activation
- Gene Editing
- Residual Nucleic Acid Removal
- Solutions
- - CytoPak Bag Solution for Closed Systems
- - CMC Production Process of Adoptive T Cell Therapies
- - CMC Production Process of Adoptive NK Cell Therapy
- - CMC Production Process of iPSC-based Cell Therapy
- - High Quality Laminin Protein Supports Clinical iPSC Banking
- - Extracellular Matrix (ECM) Proteins
- - Cytokines for Stem Cell Therapy
- - Cytokines for Organoid Culture
- - Aneuro - Neural Factors
- - Organoid Toolbox
- - Key Raw Materials for Cell & Gene Therapy
- - GMP Grade vs Premium(Pre-GMP) Grade
- - Complete Solutions from Research to Clinical Manufacturing
- Custom GMP-grade Products
- GMP-Resilient Supply
- Quality Control
- CAR Target Proteins
- Anti-Linker Antibodies
- Safety Testing Platform
- - Recombinant Factor C Endotoxin Detection Kit
- - Recombinant Factor C Endotoxin Detection Kit (High Sensitivity)Coming Soon
- - LER Sample Dilution Buffer
- - Endotoxin-Free Glass Test Tubes
- - Mycoplasma DNA Sample Preparation Kit (Magnetic beads)
- - Mycoplasma Rapid Detection Kit (qPCR)
- - Sterility Sample Preparation Kit (Magnetic beads)
- - Sterility Rapid Detection Kit (qPCR)
- - Automated Nucleic Acid Extraction System
- - Nuclease-Free Water
- - 96 V-Bottom Deep-well Plate
- - 8-Strip V-Bottom Tip Comb
- - More >>
- CMC Residue Detection Kits
- - Residual Host Cell DNA Detection Kits
- - Residual Plasmid DNA Quantitation Kit
- - RNase / DNase Detection Kits
- - Residual dsRNA ELISA Kit
- - Residual T7 RNA polymerase ELISA Kit
- - Residual BSA ELISA Kit
- - Residual Antibiotics Detection Kits
- - Residual HIV-1 p24 ELISA Kit
- - Residual Cell Culture Materials Detection Kits
- - Human Laminin Quantitative ELISA Kit
- - CGT CMC Manufacturing Process Residue Detection Solutions
- - More >>
- Flow Cytometry Analysis Platform
- - Human Th1/Th2 Cytokine Kit
- - Human TBNK 6-color Cocktail Flow Panel
- - Fluorescent Labeled CAR Target Protein
- - Anti-Linker Antibodies
- - Anti-FMC63 scFv Antibodies
- - Anti-C11D5.3 scFv Antibodies
- - MHC Tetramer
- - Antibody Labeling Kit
- - Single/Multiplex Cytokine Flow Cytometry Analysis Platform
- - Cell Phenotyping Flow Cytometry Analysis Platform
- - Star Staining New-generation Site-specific Labeling Platform
- - More >>
- Antibody Density Detection on Carriers
- - Alexa Fluor™ 488-Labeled Human CD3 epsilon Protein, His Tag
- - Alexa Fluor™ 488-Labeled Human CD8 alpha Protein, His Tag
- - Alexa Fluor™ 488-Labeled Human CD5 Protein, His Tag Star Staining
- - Alexa Fluor™ 488-Labeled Human CD4 Protein, His Tag Star Staining
- - Alexa Fluor™ 488-Labeled Human CD7 Protein, His Tag Star Staining
- - More >>
- ELISA Kits
- Functional Cell lines (Cellinsight)
- Pre-clinical Research
- Pharmacokinetics Studies
- Pharmacodynamics Studies
- Toxicity Studies
- Immunogenicity Studies
- Audit & Documentation support
- Immunohistochemistry (IHC) Antibodies
- Clinical Research
- Pharmacokinetics Studies
- Biomarker and Translational Research
- Toxicity Studies
- Immunogenicity Studies
- Immunohistochemistry (IHC) Antibodies
- In Vivo CARIn Vivo CAR
- Discovery & Development
- Antibody Density Detection on Carriers
- - Alexa Fluor™ 488-Labeled Human CD3 epsilon Protein, His Tag
- - Alexa Fluor™ 488-Labeled Human CD8 alpha Protein, His Tag
- - Alexa Fluor™ 488-Labeled Human CD5 Protein, His Tag Star Staining
- - Alexa Fluor™ 488-Labeled Human CD4 Protein, His Tag Star Staining
- - Alexa Fluor™ 488-Labeled Human CD7 Protein, His Tag Star Staining
- - More >>
- CAR Target Proteins
- Universal CAR Detection Tool
- Early Pharmacodynamic Assessment
- Safety Testing Platform
- - Recombinant Factor C Endotoxin Detection Kit
- - Recombinant Factor C Endotoxin Detection Kit (High Sensitivity)Coming Soon
- - LER Sample Dilution Buffer
- - Endotoxin-Free Glass Test Tubes
- - Mycoplasma DNA Sample Preparation Kit (Magnetic beads)
- - Mycoplasma Rapid Detection Kit (qPCR)
- - Sterility Sample Preparation Kit (Magnetic beads)
- - Sterility Rapid Detection Kit (qPCR)
- - Automated Nucleic Acid Extraction System
- - Nuclease-Free Water
- - 96 V-Bottom Deep-well Plate
- - 8-Strip V-Bottom Tip Comb
- - More >>
- Manufacturing
- Residual Nucleic Acid Removal
- Quality Control
- Antibody Density Detection on Carriers
- - Alexa Fluor™ 488-Labeled Human CD3 epsilon Protein, His Tag
- - Alexa Fluor™ 488-Labeled Human CD8 alpha Protein, His Tag
- - Alexa Fluor™ 488-Labeled Human CD5 Protein, His Tag Star Staining
- - Alexa Fluor™ 488-Labeled Human CD4 Protein, His Tag Star Staining
- - Alexa Fluor™ 488-Labeled Human CD7 Protein, His Tag Star Staining
- - More >>
- Safety Testing Platform
- - Recombinant Factor C Endotoxin Detection Kit
- - Recombinant Factor C Endotoxin Detection Kit (High Sensitivity)Coming Soon
- - LER Sample Dilution Buffer
- - Endotoxin-Free Glass Test Tubes
- - Mycoplasma DNA Sample Preparation Kit (Magnetic beads)
- - Mycoplasma Rapid Detection Kit (qPCR)
- - Sterility Sample Preparation Kit (Magnetic beads)
- - Sterility Rapid Detection Kit (qPCR)
- - Automated Nucleic Acid Extraction System
- - Nuclease-Free Water
- - 96 V-Bottom Deep-well Plate
- - 8-Strip V-Bottom Tip Comb
- - More >>
- CMC Residue Detection Kits
- Pre-clinical Research
- Pharmacokinetic Studies
- Immunogenicity Studies
- Toxicity Studies
- Immunohistochemistry (IHC) Antibodies
- Pharmacodynamic Assessment
- Clinical Research
- Pharmacokinetic Studies
- Immunogenicity Studies
- Toxicity Studies
- Immunohistochemistry (IHC) Antibodies
- Biomarker and Translational Research
- Gene TherapyGene Therapy
- Discovery & Development
- Gene Editing
- Early Pharmacodynamic Assessment
- AAV Titer Quantitation
- - AAV2 Titration ELISA Kit
- - AAV2 Titration ELISA Kit (Fast)
- - AAV3 Titration ELISA Kit
- - AAV3 Titration ELISA Kit (Fast)
- - AAV5 Titration ELISA Kit
- - AAV5 Titration ELISA Kit (Fast)
- - AAV8 Titration ELISA Kit
- - AAV8 Titration ELISA Kit (Fast)
- - AAV9 Titration ELISA Kit
- - AAV9 Titration ELISA Kit (Fast)
- Pre-existing anti-AAV Antibody Research
- Manufacturing
- Premium(Pre-GMP) grade Raw Materials
- Gene Editing Products
- Nucleic Acid Removal Products
- AAV Titer Quantitation
- - AAV2 Titration ELISA Kit
- - AAV2 Titration ELISA Kit (Fast)
- - AAV3 Titration ELISA Kit
- - AAV3 Titration ELISA Kit (Fast)
- - AAV5 Titration ELISA Kit
- - AAV5 Titration ELISA Kit (Fast)
- - AAV8 Titration ELISA Kit
- - AAV8 Titration ELISA Kit (Fast)
- - AAV9 Titration ELISA Kit
- - AAV9 Titration ELISA Kit (Fast)
- Large-Scale Manufacturing
- Quality Control
- AAV Titer Quantitation
- - AAV2 Titration ELISA Kit
- - AAV2 Titration ELISA Kit (Fast)
- - AAV3 Titration ELISA Kit
- - AAV3 Titration ELISA Kit (Fast)
- - AAV5 Titration ELISA Kit
- - AAV5 Titration ELISA Kit (Fast)
- - AAV8 Titration ELISA Kit
- - AAV8 Titration ELISA Kit (Fast)
- - AAV9 Titration ELISA Kit
- - AAV9 Titration ELISA Kit (Fast)
- Safety Testing Platform
- - Recombinant Factor C Endotoxin Detection Kit
- - Recombinant Factor C Endotoxin Detection Kit (High Sensitivity)Coming Soon
- - LER Sample Dilution Buffer
- - Endotoxin-Free Glass Test Tubes
- - Mycoplasma DNA Sample Preparation Kit (Magnetic beads)
- - Mycoplasma Rapid Detection Kit (qPCR)
- - Sterility Sample Preparation Kit (Magnetic beads)
- - Sterility Rapid Detection Kit (qPCR)
- - Automated Nucleic Acid Extraction System
- - Nuclease-Free Water
- - 96 V-Bottom Deep-well Plate
- - 8-Strip V-Bottom Tip Comb
- - More >>
- Residual Detection-resDetect
- Potency Assays
- Pre-clinical Research
- Pharmacodynamics Studies
- Immunogenicity Studies
- Toxicity Studies
- Audit & Documentation support
- Clinical Research
- Biomarker and Translational Research
- Toxicity Studies
- Immunogenicity Studies
- Therapeutic AntibodiesTherapeutic Antibodies
- Discovery & Development
- Target Proteins
- Antibody Screening
- Fc Proteins
- Cell Line (CellInsight)
- Early Pharmacodynamic Assessment
- Immunohistochemistry (IHC) Antibodies
- TR-FRET Kits
- Manufacturing
- Nucleic Acid Removal
- Quality Control
- Safety Testing Platform
- - Recombinant Factor C Endotoxin Detection Kit
- - Recombinant Factor C Endotoxin Detection Kit (High Sensitivity)Coming Soon
- - LER Sample Dilution Buffer
- - Endotoxin-Free Glass Test Tubes
- - Mycoplasma DNA Sample Preparation Kit (Magnetic beads)
- - Mycoplasma Rapid Detection Kit (qPCR)
- - Sterility Sample Preparation Kit (Magnetic beads)
- - Sterility Rapid Detection Kit (qPCR)
- - Automated Nucleic Acid Extraction System
- - Nuclease-Free Water
- - 96 V-Bottom Deep-well Plate
- - 8-Strip V-Bottom Tip Comb
- - More >>
- Residual Detection-resDetect
- Other Quality Control Products
- Cytokine Release Detection
- Preclinical Research
- Pharmacokinetics Studies
- Toxicity Studies
- Immunogenicity Studies
- Pharmacodynamics Studies
- Audit & Documentation support
- Immunohistochemistry (IHC) Antibodies
- Clinical Research
- Pharmacokinetics Studies
- Biomarker and Translational Research
- Immunogenicity Studies
- Toxicity Studies
- Immunohistochemistry (IHC) Antibodies
- Antibody Drug ConjugatesAntibody Drug Conjugates
- Discovery & Development
- Antibody Screening
- Internalization Mechanism Characterization
- Fc Effector Function Validation
- Linker Screening and Validation
- Early Pharmacodynamic Assessment
- TR-FRET Kits
- Manufacturing
- Conjugation Kits
- Quality Control
- Internalization Mechanism Characterization
- Fc Effector Function Validation
- Safety Testing Platform
- - Recombinant Factor C Endotoxin Detection Kit
- - Recombinant Factor C Endotoxin Detection Kit (High Sensitivity)Coming Soon
- - LER Sample Dilution Buffer
- - Endotoxin-Free Glass Test Tubes
- - Mycoplasma DNA Sample Preparation Kit (Magnetic beads)
- - Mycoplasma Rapid Detection Kit (qPCR)
- - Sterility Sample Preparation Kit (Magnetic beads)
- - Sterility Rapid Detection Kit (qPCR)
- - Automated Nucleic Acid Extraction System
- - Nuclease-Free Water
- - 96 V-Bottom Deep-well Plate
- - 8-Strip V-Bottom Tip Comb
- - More >>
- Residual Detection
- Enzymes for Antibody Characterization
- Antibody Characterization Services
- Pre-clinical Research
- Pharmacokinetics Studies
- Pharmacodynamics Studies
- Immunogenicity Studies
- Toxicity Studies
- Audit & Documentation support
- Immunohistochemistry (IHC) Antibodies
- Clinical Research
- Pharmacokinetics Studies
- Biomarker and Translational Research
- Toxicity Studies
- Immunogenicity Studies
- Immunohistochemistry (IHC) Antibodies
- VaccinesVaccines
- Discovery & Development
- Recombinant Viral Antigens-ViruStop
- Antigen Detection
- Vaccine Efficacy Assessment
- Early Pharmacodynamic Assessment
- Manufacturing
- Gene-editing
- Quality Control
- Antigen Detection
- Vaccine Efficacy Assessment
- Safety Testing Platform
- - Recombinant Factor C Endotoxin Detection Kit
- - Recombinant Factor C Endotoxin Detection Kit (High Sensitivity)Coming Soon
- - LER Sample Dilution Buffer
- - Endotoxin-Free Glass Test Tubes
- - Mycoplasma DNA Sample Preparation Kit (Magnetic beads)
- - Mycoplasma Rapid Detection Kit (qPCR)
- - Sterility Sample Preparation Kit (Magnetic beads)
- - Sterility Rapid Detection Kit (qPCR)
- - Automated Nucleic Acid Extraction System
- - Nuclease-Free Water
- - 96 V-Bottom Deep-well Plate
- - 8-Strip V-Bottom Tip Comb
- - More >>
- Residual Detection-resDetect
- - Vero resDNA Quantitation Kit (qPCR)
- - Pichia pastoris resDNA Quantiation Kit(qPCR)
- - Host DNA/Protein Quantitative Kits
- - RNase / DNase Detection Kits
- - GENIUS™ Nuclease Residual Detection Kit
- - Residual Raw Enzyme Materials Detection Kits
- - Residual dsRNA ELISA Kit
- - Residual BSA ELISA Kit
- - Residual Antibiotics Detection Kits
- - More >>
- Pre-clinical Research
- Clinical Research
- Vaccine Efficacy Assessment
- Toxicity Studies
- Biomarker and Translational Research
Explore by Brand- All Brands
- ServicesTechnical Service Platform
- Custom Development ServicesCustom Development ServicesMore >
- Custom GMP-grade Protein Services
- TR-FRET Kit Development Service
- MHC Complex Custom Service
- Enzyme-Linked Immunosorbent Assay (ELISA) Service
- Cell line customization service
- Recombinant Antibody Services
- Single B Cell Antibody Discovery Platform
- Anti-Idiotypic Antibody Development Service
- Analytical Testing ServicesAnalytical Testing ServicesMore >
- Biomolecular Interaction Analysis Service
- Quality Characterization Analytical Service
- Enzyme-Linked Immunosorbent Assay (ELISA) Service
- Reporter Cell Line Validation Service
- Other ServicesOther Services
- Functional Cell Line Commercial License Support
- Quality
Quality Management Systems
GMP-Resilient Supply
“Structure & Application Integrated” Protein Development Platform
- Activities
- Resources
- Supports
- ACROBiosystems
About Us
Partner with Us
Contact Us
Other Information
Menu
Home PageAll Moleculeslatent GDF-8
latent GDF-8
latent GDF-8 Overview
| English Name | Growth/differentiation factor 8 | Approved Drugs | 0 |
| Drugs in Clinical Trials | 6 | Target Synonym | MSTN，GDF-8，GDF8，Growth Differentiation Factor 8，MSLHP，Myostatin，Growth/Differentiation Factor 8 |
| Highest Development Stage | NDA/BLA | ||
| English Name | Growth/differentiation factor 8 |
| Target Synonym | MSTN，GDF-8，GDF8，Growth Differentiation Factor 8，MSLHP，Myostatin，Growth/Differentiation Factor 8 |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 6 |
| Highest Development Stage | NDA/BLA |
Product Inquiry
latent GDF-8 Background
Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions. GDF8 acts as a negative regulator of skeletal muscle growth and differentiation. In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.
latent GDF-8 Synonyms
latent GDF-8
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Talditercept alfa | RO-7239361; BMS-986089; RG-6206; BHV-2000 | Phase 3 Clinical | Bristol-Myers Squibb Company | Muscular Dystrophy, Duchenne; Neuromuscular Diseases; Muscular Atrophy, Spinal | Details |
| RO-7204239 | GYM-329; RO-7204239; RG-6237; RG-70240 | Phase 3 Clinical | F. Hoffmann-La Roche Ltd, Chugai Pharmaceutical Co Ltd | Muscular Dystrophy, Facioscapulohumeral; Muscular Atrophy, Spinal | Details |
| Trevogrumab | REGN-1033; REGN1033; SAR-391786; GDF8 | Phase 2 Clinical | Regeneron Pharmaceuticals Inc | Myositis, Inclusion Body; Obesity; Sarcopenia | Details |
| AAV1-FS344 | AAV1-Follistatin; AAV1-FS344 | Phase 2 Clinical | Nationwide Children'S Hospital | Becker muscular dystrophy; Myositis, Inclusion Body; Muscular Dystrophy, Duchenne | Details |
| KER-065 | KER-065; RKER-065 | Phase 1 Clinical | Keros Therapeutics Inc | Neuromuscular Diseases; Obesity | Details |
| HS135 | HS-135 | Phase 1 Clinical | 35Pharma Inc | Hypertension, Pulmonary; Heart Failure, Diastolic; Pulmonary Arterial Hypertension | Details |
- Overview
- Product Inquiry
- Clinical Drug Information
Share to:
Online Message
Contact Us
[North America]: +1 800-810-0816
[Switzerland]: +41 800 040 012
[Asia & Pacific]: +86 400-682-2521
[North America]: 1 Innovation Way, Newark, DE 19711, USA
[Switzerland]: ACRObiosystems AG, c/o Zug Dammstrasse Centre AG, Dammstrasse 19, 6300 Zug Switzerland