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Monoclonal Anti-C11D5.3 scFv Antibody, Mouse lgG1 (3G8C1) (Carrier-free) (recommended for ADA assay)

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C13-MY2010b-25ug

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C13-MY2010b-100ug

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Product Details
Performance Data
Reviews & Citations
Important Statement
Resources

Source

Monoclonal Anti-C11D5.3 scFv Antibody, Mouse IgG1 (3G8C1) is a non-neutralizing mouse monoclonal antibody recombinantly expressed from HEK293 cells.

Antibody Type

Recombinant Monoclonal

Clone

3G8C1

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Reactivity

Mouse

Immunogen

Recombinant Mouse C11D5.3 scFv derived from HEK293 cells

Specificity

Specifically recognizes C11D5.3 derived CARs.

Application

Application	Recommended Use / Performance
ELISA	0.2-2 μg/mL

Purification

Protein A purified.

Aggregation

Less than 10%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

The product MUST be stored at -70°C or lower upon receipt;
-70°C for 12 months under sterile conditions.

Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

QMS(ISO, GMP)

Quality Advantages

Quality Control Process

Background

C11D5.3 is an IgG1 mouse monoclonal antibody specific for BCMA, which is a target for the immunotherapy of multiple myeloma and lymphomas. C11D5.3 scFv is the most commonly used ectodomain componse of BCMA-specific CARs. So far, multiple reported CART BCMA trials contain the anti-BCMA scFv derived from C11D5.3, such as FDA approved CARs Abecma.