ASGR1

ASGR1

ASGR1 Overview

Molecule Name
Asialoglycoprotein receptor 1
Synonyms
ASGP-R 1, ASGPR 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, HL-1
Drug Development Progress
Drugs in Clinical Trials1
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
HL-1,C-type lectin domain family 4 member H1,Hepatic lectin H1,ASGPR 1,ASGR1,Asialoglycoprotein Receptor 1,CLEC4H1,ASGP-R 1,ASGPR1
Background
ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2). ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.

ASGR1 Product List

Species
  • Human(3)
  • Cynomolgus(2)
  • Mouse(2)
  • Rat(1)
Tag
  • Fc Tag(4)
  • His Tag(3)
  • His Tag & Avi Tag(1)
Host
  • HEK293(8)
Conjugate
  • Unconjugated(7)
  • Biotin-labeled(1)
Grade
  • RUO(8)
Low Endotoxin
  • Yes(6)
  • No(2)
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&PriceAdd to Cart
ASGR1
Human ASGR1 / ASGPR1 Protein, Fc Tag, low endotoxin (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISABLI

$395.00

100ug
ASGR1
Human ASGR1 / ASGPR1 Protein, His Tag, low endotoxin (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISASPR

$415.00

100ug
ASGR1
Mouse ASGR1 Protein, His Tag, low endotoxin (MALS verified)
Mouse
HEK293
MALSSDS-PAGE

$470.00

100ug
ASGR1
HOTAvitag
GS1-H82Q3
Biotinylated Human ASGR1 / ASGPR1 Protein, His,Avitag™
Human
HEK293
SDS-PAGE
ELISABLI

$650.00

25ug
ASGR1
Cynomolgus ASGR1 Protein, His Tag, low endotoxin
Cynomolgus
HEK293
SDS-PAGE
ELISA

$395.00

100ug
ASGR1
Cynomolgus ASGR1 Protein, Fc Tag, low endotoxin
Cynomolgus
HEK293
SDS-PAGE
ELISA

$395.00

100ug
ASGR1
Mouse ASGR1 Protein, Fc Tag, low endotoxin (MALS verified)
Mouse
HEK293
MALSSDS-PAGE
SPR

$410.00

100ug
ASGR1
Rat ASGR1 / ASGPR1 Protein, Fc Tag
Rat
HEK293
SDS-PAGE
ELISA

$410.00

100ug
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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Kylo-11Kylo-11; Kylo11Phase 2 ClinicalShanghai Hejiya Biopharmaceutical Co Ltd, Xiamen Ganbaoli Biopharmaceutical Co Ltd
Atherosclerosis; Cardiovascular Diseases; Hyperlipoproteinemias; Lipid Metabolism Disorders
Details
Customer Reviews
  • N***i2024-11-25
    I recently purchased the hASGPR protein from Acro Biosystems for use in my SPR (surface plasmon resonance) experiments, and I am thrilled with the results! The protein quality was excellent, and it delivered reliable and reproducible data, which significantly boosted the confidence in my study. The purity and functional activity of the hASGPR were clearly top-notch, making it easy to work with and yielding strong, clean sensorgrams. I am particularly impressed with how well it performed in terms of binding affinity and kinetics analysis, which was a critical aspect of my research. Shipping was also quick, and the product was well-packaged to maintain its integrity. Overall, I highly recommend this product to anyone conducting SPR experiments requiring hASGPR. Great product and great experience!