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Home PageAll MoleculesBDNF
BDNF
BDNF Overview
| English Name | Brain-derived neurotrophic factor | Approved Drugs | 1 |
| Drugs in Clinical Trials | 8 | Target Synonym | Brain-Derived Neurotrophic Factor，Abrineurin，ANON2，Brain Derived Neurotrophic Factor，BULN2，ProBDNF，Neurotrophin |
| Highest Development Stage | Phase 3 Clinical | ||
| English Name | Brain-derived neurotrophic factor |
| Target Synonym | Brain-Derived Neurotrophic Factor，Abrineurin，ANON2，Brain Derived Neurotrophic Factor，BULN2，ProBDNF，Neurotrophin |
| Approved Drugs | 1 |
| Drugs in Clinical Trials | 8 |
| Highest Development Stage | Phase 3 Clinical |
BDNF Product List
- Product Category
Protein (4)
- Product Status
Launched (4)
- Species
Human (4)
- Tag
Tag Free (4)
- Conjugate
Unconjugated (4)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
BDF-H5116 |  Human | E. coli | Human BDNF / Abrineurin Protein (E. coli), premium grade |  |  |  |  Add to Cart |
BDF-H5117 | Human | E. coli | Human BDNF / Abrineurin Protein (E. coli), Research Grade |  | | Add to Cart | |
BDF-H5219 | Human | HEK293 | Human BDNF / Abrineurin Protein (HEK293), premium grade |  | |  | Add to Cart |
GMP-BDFH15 | Human | E. coli | GMP Human BDNF Protein (E. coli) |  | | Add to Cart |
Total: 4
- 1
BDNF Background
Brain-derived neurotrophic factor (BDNF) along with nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5) are members of the neurotrophin family of trophic factors. The neurotrophins play essential roles in the development, survival, and function of a wide range of neurons in both the peripheral and central nervous systems. The neurotrophins interact with two cell surface receptors, the low affinity P75 receptor and the Trk family of high affinity tyrosine kinase receptors. NGF preferentially binds TrkA, BDNF and NT4/5 bind TrkB, and NT-3 binds TrkC (and TrkA to a lesser extent).
BDNF Synonyms
BDNF,ANON2,BULN2,Abrineurin
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Tetramethylpyrazine Nitrone | Phase 3 Clinical | Jinan University | Diabetes Mellitus, Type 2; Stroke; Diabetic Nephropathies; Amyotrophic Lateral Sclerosis | Details | |
| ACT-01 | ACT-01; OCS-05; BN-201; G-79 | Phase 2 Clinical | Promius Pharma | Keratosis, Actinic; Optic Neuritis; Demyelinating Diseases | Details |
| MP-101 | MP101; MP-101 | Phase 2 Clinical | Mitochon Pharmaceuticals | Multiple Sclerosis; Huntington Disease; Amyotrophic Lateral Sclerosis | Details |
| ALTO-100 | ALTO-100 | Phase 2 Clinical | Alto Neuroscience Inc | Depressive Disorder, Major; Bipolar I Disorder; Stress Disorders, Post-Traumatic; Bipolar II Disorder | Details |
| AC-102 | AC-102 | Phase 2 Clinical | AudioCure Pharma GmbH | Tinnitus; Hearing Loss, Sensorineural; Hearing Loss, Sudden | Details |
| TTI-0102 | TTI-0102 | Phase 2 Clinical | Va Office Of Research And Development | Rett Syndrome; Leigh Disease; Metabolic Dysfunction-Associated Steatotic Liver Disease; MELAS Syndrome; Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult; Stress Disorders, Post-Traumatic | Details |
| JS1-1-01 | JS1-1-01 | Phase 2 Clinical | Tianjin Tasly Pharmaceutical Co Ltd | Depression; Depressive Disorder, Major; Depressive Disorder | Details |
| AAV2-BDNF gene therapy (University Of California San Diego) | Phase 1 Clinical | University Of California San Diego | Alzheimer Disease; Cognitive Dysfunction | Details |
Marketed Drug Information
| English Name | Research Code | Highest Development Stage | Company | Earliest Brand Name | Earliest Approval Country | Earliest Indication | Earliest Approval Company | Earliest Approval Date | Indication | Clinical Trial |
|---|---|---|---|---|---|---|---|---|---|---|
| Laquinimod Sodium | TV-5600; ABR-215062; SAIK-MS | Approved | Active Biotech Ab | Nerventra | Multiple Sclerosis, Relapsing-Remitting; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Huntington Disease; Arthritis; Uveitis; Eye Diseases; Crohn Disease | Details |
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