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CCL2

CCL2 Overview

English NameC-C motif chemokine 2Approved Drugs1
Drugs in Clinical Trials3Target SynonymMCP1，HC11，Monocyte chemotactic protein 1，Monocyte chemoattractant protein 1，CCL2，C-C Motif Chemokine Ligand 2，Monocyte Chemotactic And Activating Factor，Monocyte Secretory Protein JE，Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je)，Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 2，Monocyte Chemoattractant Protein-1，Chemokine (C-C Motif) Ligand 2，Small-Inducible Cytokine A2，SCYA2，MCP-1，MCAF，Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je，C-C Motif Chemokine 2，HSMCR30，GDCF-2，SMC-CF，Chemokine CCL2，MGC9434
Highest Development StageApproved
English NameC-C motif chemokine 2
Target SynonymMCP1，HC11，Monocyte chemotactic protein 1，Monocyte chemoattractant protein 1，CCL2，C-C Motif Chemokine Ligand 2，Monocyte Chemotactic And Activating Factor，Monocyte Secretory Protein JE，Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je)，Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 2，Monocyte Chemoattractant Protein-1，Chemokine (C-C Motif) Ligand 2，Small-Inducible Cytokine A2，SCYA2，MCP-1，MCAF，Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je，C-C Motif Chemokine 2，HSMCR30，GDCF-2，SMC-CF，Chemokine CCL2，MGC9434
Approved Drugs1
Drugs in Clinical Trials3
Highest Development StageApproved

CCL2 Product List

  • Product Category

    Protein (1)Kits (1)

  • Product Status

    Launched (2)

  • Species

    Human (2)

  • Tag

    Fc Tag (1)- (1)

  • Conjugate

    Unconjugated (1)- (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
CC2-H5255
Human
HEK293
Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified)
CEA-B036
Human
-
Human MCP-1 / CCL2 ELISA Kit
Total: 2
  • 1

CCL2 Background

Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. CCL2, a member of the CC subfamily, is characterized by two adjacent cysteine residues. CCL2 displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

CCL2 Synonyms

CCL2,C-C motif chemokine 2,MCP-1,MCAF

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
AFX-5931AFX-5931Phase 2 ClinicalAfecta Pharmaceuticals IncEczema
Details
MW-151MW01-9-034WH; MW-151; MW01-2-151SRMPhase 1 ClinicalUniversity Of KentuckyDrug-Related Side Effects and Adverse Reactions; Poisoning; Cognition Disorders
Details
64CU-DOTA-ECL1iPhase 1 ClinicalWashington University School Of MedicineCarotid Artery Diseases; Heart Diseases; Arteriosclerosis
Details

Marketed Drug Information

English NameResearch CodeHighest Development StageCompanyEarliest Brand NameEarliest Approval CountryEarliest IndicationEarliest Approval CompanyEarliest Approval DateIndicationClinical Trial
PropagermaniumSK-818; SK-818CApprovedSanwa Kagaku Kenkyusho Co LtdSerocionJapanHepatitis BSanwa Kagaku Kenkyusho Co Ltd1994-01-01Hepatitis B
Details
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  • Product List
  • Marketed Drug Information
  • Clinical Drug Information
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