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GITR

GITR

GITR Overview

Molecule Name
Glucocorticoid-induced tumor necrosis factor receptor-related protein
Synonyms
AITR,GITR,TNFRSF18,CD357
Drug Development Progress
Drugs in Clinical Trials4
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18
Background
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

GITR Product List

Species
  • Human（4）
  • Mouse（2）
  • Canine（1）
Tag
  • His Tag（3）
  • His Tag & Avi Tag（2）
  • Fc Tag（1）
  • Fc Tag & Avi Tag（1）
Host
  • HEK293（7）
Conjugate
  • Unconjugated（4）
  • Biotin-labeled（3）
Grade
  • RUO（7）
Low Endotoxin
  • Yes（2）
  • No（5）
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&PriceAdd to Cart
GITR
HOT
GIR-H5228
Human GITR / TNFRSF18 Protein, His Tag, low endotoxin (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$345.00

100ug
GITR
HOT
GIR-H5254
Human GITR / TNFRSF18 Protein, Fc Tag, low endotoxin
Human
HEK293
SDS-PAGE
ELISA

$340.00

100ug
GITR
GIR-C52H6
Canine GITR / TNFRSF18 Protein, His Tag
Canine
HEK293
SDS-PAGE
ELISA

$360.00

100ug
GITR
Avitag
GIR-H82E5
Biotinylated Human GITR / TNFRSF18 Protein, His,Avitag™ (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$360.00

25ug
GITR
Avitag
GIR-H82F7
Biotinylated Human GITR / TNFRSF18 Protein, Fc,Avitag™
Human
HEK293
SDS-PAGE
ELISA

$360.00

25ug
GITR
GIR-M52H3
Mouse GITR / TNFRSF18 Protein, His Tag
Mouse
HEK293
SDS-PAGE
ELISA

$360.00

100ug
GITR
Avitag
GIR-M82E3
Biotinylated Mouse GITR / TNFRSF18 Protein, His,Avitag™ (MALS verified)
Mouse
HEK293
MALSSDS-PAGE
ELISA

$3675.00

25ug
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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
BMS-986156BMS-986156Phase 2 ClinicalBristol-Myers Squibb Company
Liver Neoplasms; Lung Neoplasms; Neoplasms; Solid tumours; Thoracic Neoplasms
Details
RagifilimabINCAGN-1876; INCAGN-01876; AGEN-1876; CM-701Phase 2 ClinicalAgenus Inc, Ludwig Institute For Cancer Research
Neoplasm Metastasis; Neoplasms
Details
Anti-GITR antibody (BMS)Phase 1 ClinicalBristol-Myers Squibb Company
Neoplasms
Details
IBI-102IBI102; IBI-102Phase 1 Clinical
Neoplasms
Details
Customer Reviews
  • 1***32019-09-27
    Human GITR / TNFRSF18 Protein, His Tag, low endotoxin (MALS verified)
    I have been using Acro's products for a long time. Whenever there is some concerns on product or technical support is needed, it always gets solved in time. I used the GITR protein for SPR experiments. I have done 6 concentration gradients, and the fitted curve was still very good. The data also met my expectations. I hope we will continue having a good cooperation with ACRO moving forward.