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Jagged 1

Jagged 1

Jagged 1 Overview

Molecule Name
Protein jagged-1
Synonyms
CD339,JAG1,Jagged1,hJ1,JAGL1
Drug Development Progress
Drugs in Clinical Trials2
Approved Drugs0
Highest Development StagePhase 1 Clinical
Target Synonym
AHD，AWS，AGS，Jagged-1 Protein，Jagged1，Protein jagged-1，JAG1，Jagged 1，JAGL1，Alagille Syndrome，CD339，AGS1，DCHE，Jagged Canonical Notch Ligand 1，hJ1，CD339 Antigen
Background
Protein jagged-1 (JAG1) is also known as Jagged1, hJ1, JAGL1 and CD339, which is a single-pass type I membrane protein containing one DSL domain and 15 EGF-like domains. JAG1 is widely expressed in adult and fetal tissues,the expression of JAG1 is up-regulated in cervical squamous cell carcinoma and also expressed in bone marrow cell line HS-27a.JAG1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. JAG1 is involved in early and late stages of mammalian cardiovascular development. JAG1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro).

Jagged 1 Product List

Species
  • Human（1）
Tag
  • His Tag（1）
Host
  • HEK293（1）
Conjugate
  • Unconjugated（1）
Grade
  • RUO（1）
Low Endotoxin
  • Yes（1）
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&PriceAdd to Cart
Jagged 1
JA1-H52H9
Human Jagged 1 / JAG1 Protein, His Tag, low endotoxin
Human
HEK293
SDS-PAGE
SPR

$300.00

50ug
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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
AMG-430AMG-430Phase 1 ClinicalAmgen Inc
Cystic Fibrosis; Pulmonary Disease, Chronic Obstructive
Details
ART-104 (Arnatar Therapeutics)ART-104; ART104ClinicalSuzhou Arnatar Therapeutics Co Ltd
Alagille Syndrome
Details
Customer Reviews
  • n***l2026-08-08
    Human Jagged 1 / JAG1 Protein, His Tag, low endotoxin
    This product genuinely is the best and i have been using it for a while and it's been nothing but amaizng
  • V***s2021-08-25
    Human Jagged 1 / JAG1 Protein, His Tag, low endotoxin
    We are a company in the filed of Antibody Discovery and engineering.. Jagged 1/JAG1 His tag shelps us greatly in searching and characterization of specific antibodies,and detectors. It is a great quality product, and its efficacy is always reliable. It also comes with a certification of analysis, which has very insighful information. We use Acrobiosystems products, because they are easy to order, reliable and fast delivery. Thank you! Victor G.