Ly6E

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Ly6E Overview

Molecule Name

Lymphocyte antigen 6E

Synonyms

LY6E,Ly-6E,Ly6E,RIG-E,SCA-2,TSA-1,9804,RIGE,SCA2,TSA1

Drug Development Progress

Drugs in Clinical Trials1

Approved Drugs0

Highest Development StagePhase 1 Clinical

Target Synonym

TSA-1，Retinoic acid-induced gene E protein，SCA-2，TSA1，Ly-6E，RIG-E，RIGE，Stem cell antigen 2，LY6E，Lymphocyte Antigen 6 Family Member E，Retinoic Acid Induced Gene E，Thymic Shared Antigen 1，SCA2，Lymphocyte Antigen 6E，9804，Lymphocyte Antigen 6 Complex， Locus E

Background

This gene belongs to the human Ly6 gene family and encodes a glycosylphosphatidyl-inositol (GPI)-anchored cell surface protein. The protein plays an important role in T cell physiology, oncogenesis and immunological regulation. The protein is also involved in modulation of viral infection by coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2