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Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (MALS verified)

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Cat. No. / Size
Price
Qty
HRV-M720-100ug
$415.00
HRV-M720-1mg
$2735.00
ETA of in-stock products:2 business days
Sub-Total$ 0

Product Details

  • Source

    Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human constant domain.

  • Clone

    hRSV90

  • Isotype

    Human IgG1 | Human Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Recombinant Monoclonal

  • Specificity

    This product is a specific antibody specifically reacts with HRSV F.

  • Application

    Application
    Recommended Usage
    ELISA
    0.03-313 ng/mL
  • Purity

    90% as determined by SDS-PAGE.

    95% as determined by SEC-MALS.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Supplied a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 12 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    Prefusion glycoprotein F0/pre-F protein (RSV) SDS-PAGE

    Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Prefusion glycoprotein F0/pre-F protein (RSV) SEC-MALS

    The purity of Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (Cat. No. HRV-M720) is more than 95% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     Prefusion glycoprotein F0/pre-F protein (RSV) ELISA

    Immobilized HRSV (A) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H7) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (Cat. No. HRV-M720) with a linear range of 0.03-1 ng/mL. HRSV (A) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H6) is verified not recoginized by Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (Cat. No. HRV-M720) in low concentration (QC tested).

    Protocol
  •  Prefusion glycoprotein F0/pre-F protein (RSV) ELISA

    Immobilized HRSV (B) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H8) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (Cat. No. HRV-M720) with a linear range of 0.03-1 ng/mL. HRSV (B) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H9) is verified not recoginized by Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (Cat. No. HRV-M720) in low concentration (Routinely tested).

    Protocol

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Background

Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single‑chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post‑fusion conformation. The antibody hRSV90 recognizes a prefusion‑specific epitope encompassing residues 163–181 within antigenic site V on the RSV F protein.

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