Human CCL17 / TARC Protein, Fc Tag (MALS verified)

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Cat. No. / Size
Price
Qty
CC7-H5256-20ug
$185.00
CC7-H5256-50ug
$370.00
CC7-H5256-1mg
$3400.00
ETA of in-stock products:2 business days

Product Details

  • Synonym

    TARC, ABCD-2, SCYA17, A-152E5.3

  • Source

    Human CCL17, Fc Tag (CC7-H5256) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 94 (Accession # Q92583-1).

    Predicted N-terminus: Ala 24

    Request for sequence
  • Molecular Characterization

    CCL17 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 34.5 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100mM Gly, 25mM Arginine, 150mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    CCL17 SDS-PAGE

    Human CCL17, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • SEC-MALS

    CCL17 SEC-MALS

    The purity of Human CCL17, Fc Tag (Cat. No. CC7-H5256) is more than 95% and the molecular weight of this protein is around 80-108 kDa verified by SEC-MALS.

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Background

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

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