Product Details
Synonym
C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CC-CKR-2CKR2B, CCR2, CCR-2, CCR2A, CCR2B, CD192 antigen, CD192, chemokine (C-C motif) receptor 2, CKR2, CKR2A, CMKBR2, CMKBR2MGC111760, FLJ78302, MCP-1 receptor, MCP-1-R, MCP-1-RMGC103828, MGC168006, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor
Source
Human CCR2 Full Length Protein, Flag,His Tag (CC2-H52D4) is expressed from human 293 cells (HEK293). It contains AA Leu 2 - Ala 374 (Accession # P41597-1).
Predicted N-terminus: Asp
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a flag tag at the N-terminus and a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 45.3 kDa.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>85% as determined by SDS-PAGE.
Formulation
This product is not suitable for cell based experiments due to cytotoxicity of DDM.
DDM and CHS are INDISPENSABLE to keep membrane protein soluble and active, under no circumstances should you remove DDM and CHS.
DDM/CHS buffer (DC-11) is sold separately and not included in protein, and please contact us if you need the buffer.
If glycerol is not compatible with your application, remove glycerol just before the immediate experiment, and NEVER store glycerol-free protein solution.Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 with glycerol as protectant.
Contact us for customized product form or formulation.
Shipping
This product is supplied and shipped with dry ice, please inquire the shipping cost.
Storage
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- The product MUST be stored at -70°C or lower upon receipt;
- -70°C for 3 months under sterile conditions.
ACRO Quality Management System
- *The DDM/CHS buffer (Cat. No. DC-11) is sold separately and not included in protein, you can follow this link for product information.
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Performance Data
Bioactivity-ELISA

Immobilized Human CCR2 Full Length Protein, Flag,His Tag (Cat. No. CC2-H52D4) at 1 μg/mL (100 μL/well) can bind Anti-CCR2 antibody with a linear range of 0.6-39 ng/mL (QC tested).
Protocol
Bioactivity-SPR

Anti-CCR2 antibody captured on Protein A Chip can bind Human CCR2 Full Length Protein, Flag,His Tag (Cat. No. CC2-H52D4) with an affinity constant of 205 nM as determined in a SPR assay (in presence of DDM and CHS) (Biacore 8K) (Routinely tested).
Protocol
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